This is a chronic blistering disease which occurs in children. It usually
starts before the age of 5 years. Small and large blisters appear predominantly
on the lower trunk, genital area and thighs, often also on the
scalp and around the mouth. They may spread all over the body. New
blisters form around healing old blisters, forming "a cluster of jewels".
There is often some itchiness. The course is chronic, spontaneous remission
usually occurs after an average of 3-4 years.
Management of chronic bullous dermatosis of childhood
- Dapsone in doses from 12,5 to 125 mg daily or Sulphapyridine 250 mg to 3 grams
daily usually control the eruption. After it clears you can slowly reduce the dosage to
a maintenance dose but you may need to increase it again when disease activity
flares up.
- Treat any superinfection with betadine, GV paint or if severe antibiotics.
- If there is no response to the above treatment, topical (strong) or systemic corticosteroids
may need to be added. Take care not to overtreat, especially regarding the
side effects of systemic steroids in children.
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